Document Library and Dental/MedicalOver the last several years the use of a monolithic IPS e.max® lithium disilicate restoration has rapidly increased. Clinicians, laboratories and researchers have suggested its use as an alternative to porcelain fused to metal due to its high durability. Though lithium disilicate is extremely resistant to fracture, it has been shown to also be kind to opposing dentition. The high wear compatibility of IPS e.max lithium disilicate with natural dentition has been demonstrated in several in-vitro studies both internally as well as through third parties. Recently, an in vivo study by Dr. Josephine Esquivel-Upshaw at the University of Florida investigated the wear rates experienced intra-orally with lithium disilicate. While the in-vitro studies show great wear compatibility from a material properties perspective, the in-vivo research validates the real life application of the product.